|
|
 |
|
The Microbicides Development Programme (MDP) is a partnership set up:
- to determine the scientific mechanisms underlying the activity of microbicidal agents;
- to conduct pre-clinical evaluation of potential microbicides;
- to undertake Phase I and Phase II (if
appropriate) studies of new products and combinations in healthy female
volunteers and women with HIV infection;
- to compare different products and
formulations in healthy female volunteers in terms of their
cervico-vaginal distribution and retention by imaging;
- to undertake feasibility studies and Phase II microbicide trials as a prelude to Phase III studies;
- to undertake in Africa a multinational Phase III, randomised, double blind, placebo controlled trial of candidate compounds;
- to address issues raised by the
availability of an effective microbicide in relation to their
widespread introduction, through collaborations with behavioural
scientists, health economists, social marketing specialists and
mathematical modellers;
- to explore issues surrounding
affordable microbicidal products for the developing world, including by
developing relationships with pharmaceutical and biotech companies.
The MDP is co-ordinated jointly by the MRC Clinical
Trials Unit and Imperial College at St
Mary’s Hospital.
In addition to the MRC Clinical Trials Unit and Imperial College, the MDP partners are:
In addition to the MRC Clinical Trials Unit and Imperial College,
the MDP partners are:
|
|
|
AMREF/NIMR, Mwanza, Tanzania
|
| Medical Research Council (South Africa), Durban, South Africa |
Reproductive Health and HIV Research Unit, University of the Witwatersrand,
Johannesburg, South Africa |
| The Africa Centre for Health and Population Studies, South Africa |
| MRC/Uganda Virus Research Institute, Entebbe, Uganda |
| University
Teaching Hospital, Lusaka, Zambia |
| Manhica/INS/FDC, Maputo/Manhica, Mozambique |
|
|
| London School of Hygiene and Tropical Medicine |
| MRC Social and Health Public Sciences Unit, University of Glasgow |
| St George’s
Hospital Medical School |
| University of Southampton |
| University of Barcelona |
| University of York |
| Oxford University |
|
|
|
