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The main MDP site is in Entebbe, on the
site of the Uganda Virus Research Institute, and there
are a number of rural field stations including Masaka,
which is South West of Entebbe.
The MDP works within the MRC Programme on AIDS, which
was established in 1988 following a request from the Ugandan
Government to the British Government for assistance with
AIDS.
The population for the trial is HIV discordant couples
from a general population, and a smaller number of concordant
negative couples. These are drawn from 25 villages, with
a total population of approximately 15,500. The population
had been previously surveyed in 2000 as part of the Masaka
Intervention Trial.
The Co-Principle Investigators are Dr Anatoli Kamali,
who has been working in the Masaka district for 15 years,
and Professor Heiner Grosskurth, who is the Director of the MRC
Programme.
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