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To determine the scientific mechanisms underlying the activity of microbicides
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To conduct pre-clinical evaluation of potential microbicides in in vitro models
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To undertake early clinical studies of new microbicide products and combinations of products in UK and African populations
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To explore the distribution and retention of microbicide products and formulations
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To prepare clinical trial sites through feasibility studies as a prelude to multi-national, randomised, double-blind, controlled trials of candidate microbicides in Africa
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To optimise the tools and procedures and to understand the way in which the products are used within the study and broader population
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To provide economic and epidemiological support to implement the widespread use of any product shown to be effective in the clinical trials. |
